AMPK (alpha1, beta1, gamma1), active

Recombinant, human AMPK (α1, β1, γ1) holoenzyme, comprised of full length N-terminal 6His-tagged AMPKα1, full length untagged AMPKβ1 and full length untagged AMPKγ1.

Catalog #: 14-840


Biological Information
Background Information:
AMPK (α1, β1, γ1) protein belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed. GenBank AF100763 / GenBank NM_006253 / GenBank NM_002733
Target Class:
Accession Number:
AF100763; NM_006253; NM_002733
Target Name:
AMPK (α1, β1, γ1)
Target Aliases:
Target Species:
Product Type:
Drug Discovery & Development
Storage Conditions:
6 months at -70°C
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14-840x Datasheet

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