| Biological Information | |
|---|---|
| Background Information: | On ligand binding, ALK4 forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators.
GenBank NM_004302 |
| Target Class: | Kinase |
| Family: | Receptor Tyrosine Kinase (RTK): Type XIX RTK: Leukocyte tyrosine kinase (LTK) Receptor family |
| Accession Number: | NM_004302.3; NM_020327.2; NM_020328.2 |
| Target Name: | ALK4 |
| Target Aliases: | ACVR1B, ALK-4, ACVRLK4, ALK4, SKR2, ActRIB, ACTR-IB, ACTRIB |
| Target Species: | Human |
| Usage | |
| Product Type: | Enzymes |
| Application: | Drug Discovery & Development |
| Storage Conditions: | 6 months at -70°C |
| Usage Disclaimer: | These products may be covered by issued US and/or foreign patents, patent application and subject to Limited Use Label License. Please visit discoverx.com/license for a list of products that are governed by limited use label license terms and relevant patent and trademark information. |
ALK4, active
N-terminal GST-tagged recombinant, human ALK4 amino acids 150-end.
Datasheets
14-614x Datasheet
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