| Biological Information | |
|---|---|
| Background Information: | This proto-oncogene belongs to the RAF subfamily of the Ser/Thr protein kinase family, and maybe involved in cell growth and development. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
GenBank U01337.1 The recombinant protein contains the amino acid substitution Y301D and Y302D with reference to GenBank U01337.1. These mutations provide constitutive activation of the enzyme. |
| Target Class: | Kinase |
| Family: | Ser/Thr Kinase |
| Accession Number: | U01337.1 |
| Target Name: | A-Raf |
| Target Species: | Human |
| Usage | |
| Product Type: | Enzymes |
| Application: | Drug Discovery & Development |
| Storage Conditions: | 1 year at -70°C |
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A-Raf, active
N-terminal GST-tagged recombinant, human A-Raf amino acids 273-end containing the mutations Y301D and Y302D.
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14-956x Datasheet
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