TLK2, active

Background Information:

The Tousled-like kinases, first described in Arabidopsis, are nuclear serine/threonine kinases that are potentially involved in the regulation of chromatin assembly. Rapidly and transiently inhibited by phosphorylation following the generation of DNA double-stranded breaks during S- phase. This is cell cycle checkpoint and ATM-pathway dependent and appears to regulate processes involved in chromatin assembly. GenBank BC044925

Target Class:

Kinase

Family:

Other Protein Kinase

Sub Family:

Protein Ser/Thr

Protein Name:

TLK2

Protein Aliases:

HsHPK|PKU-alpha|Tousled-like kinase 2

Accession Number:

NM_006852.2

UniProt Number:

Q86UE8

Gene Name:

TLK2

Gene ID:

11011

Gene Aliases:

PKU-ALPHA|MGC44450

Target Species:

Human