STK25, active

Background Information:

STK25 is a member of the germinal center kinase III (GCK III) subfamily of the sterile 20 superfamily of kinases. The enzyme plays a role in serine-threonine liver kinase B1 (LKB1) signaling pathway to regulate neuronal polarization and morphology of the Golgi apparatus. The protein is translocated from the Golgi apparatus to the nucleus in response to chemical anoxia and plays a role in regulation of cell death. A pseudogene associated with this gene is located on chromosome 18.

Target Class:

Kinase

Family:

STE

Sub Family:

Protein Ser/Thr

Protein Name:

YSK1

Protein Aliases:

Ste20-like kinase|Sterile 20/oxidant stress-response kinase 1|SOK-1|Ste20/oxidant stress response kinase 1

Accession Number:

NM_006374

UniProt Number:

O00506

Gene Name:

STK25

Gene ID:

10494

Gene Aliases:

SOK1|YSK1

Target Species:

Human