Src, active

Background Information:

Src family tyrosine kinases are non-receptor tyrosine kinases that are functionally linked to some receptor-type tyrosine kinases, G-protein-coupled receptors, cytokine receptors, and cell adhesion molecules/receptors. Src family tyrosine kinases are membrane-associated proteins having Src homology 2 (SH2) and SH3 domains, which are important for protein-protein interaction. The activity of Src family tyrosine kinases is regulated through intramolecular interaction between the SH2 domain and the phosphorylated tyrosine at the C-terminal regulatory site (Tyr-527). EMBL K03218

Target Class:

Kinase

Family:

TK

Sub Family:

Protein Tyrosine

Protein Name:

Src

Protein Aliases:

Proto-oncogene c-Src|pp60c-src|p60-Src

Accession Number:

NM_005417.3; NM_198291.1

UniProt Number:

P12931

Gene Name:

SRC

Gene ID:

6714

Gene Aliases:

ASV|c-src

Target Species:

Human