SMG1, active

Background Information:

Full length, active recombinant SMG1 expressed in a mammalian cell line. SMG1 is a serine/threonine protein kinase belonging to the PI3/PI4-kinase family. It is known to play key roles in mRNA surveillance and genotoxic stress response pathways. The kinase has been linked to various cancers including multiple myeloma, head and neck squamous cell carcinoma and acute myeloid leukemia.

Target Class:

Kinase

Family:

PI3/PI4-kinase

Sub Family:

Serine/threonine kinase

Protein Name:

SMG1

Protein Aliases:

SMG1 nonsense mediated mRNA decay associated PI3K related kinase

Accession Number:

Genbank NM_015092.4

UniProt Number:

Q96Q15

Gene Name:

SMG1

Gene ID:

23049

Gene Aliases:

ATX; LIP; 61E3.4

Target Species:

Human