Biological Information

Background Information:

RPTPµ is a receptor protein-tyrosine phosphatase that mediates homotypic cell-cell interactions and plays a role in adipogenic differentiation via modulation of p120 catenin/CTNND1 phosphorylation. Promotes CTNND1 dephosphorylation and prevents its cytoplasmic localization where it inhibits SLC2A4 membrane trafficking. In turn, SLC2A4 is directed to the plasma membrane and performs its glucose transporter function. GenBank NM_002845

Target Class:

Phosphatase

Family:

RTP

Sub Family:

Protein Tyrosine

Protein Name:

PTPRM

Accession Number:

NM_002845

UniProt Number:

P28827

Gene Name:

PTPRM

Gene ID:

5797

Gene Aliases:

RPTPU|hR-PTPu

Target Species:

Human

Usage

Product Type:

Enzymes

Application:

Drug Discovery & Development

Storage Conditions:

1 year at -70°C

Usage disclaimer:

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Assay Information

Assay Type:

Enzymatic

Bioassay Data

Trademark Statement:

For Research Use Only