RIPK2, active

Background Information:

RIPK2 (receptor-interacting serine-threonine kinase 2, RIP2, RICK, CARD3, CARDIAK) is a death domain-containing serine-threonine kinase associated with TNF receptor and implicated in the activation of NF-kappaB and cell death in mammalian cells. RIPK2 represents a kinase that regulates TNF and Fas induced-apoptosis and that is involved in the generation of pro-inflammatory cytokine IL-1β. GenBank NM_003821

Target Class:

Kinase

Family:

TKL

Sub Family:

Protein Ser/Thr

Protein Name:

RIPK2

Protein Aliases:

CARD-containing interleukin-1 beta-converting enzyme-associated kinase|CARD-containing IL-1 beta ICE-kinase|RIP-like-interacting CLARP kinase|Receptor-interacting protein 2|RIP-2|Tyrosine-protein kinase RIPK2

Accession Number:

NM_003821.5

UniProt Number:

O43353

Gene Name:

RIPK2

Gene ID:

8767

Gene Aliases:

RICK|RIP2|CARDIAK|CARD3

Target Species:

Human