Biological Information
Background Information:
4-1BB-L, also called CD137L or TNFSF9, is a transmembrane glycoprotein belonging to the TNF superfamily and is involved in reverse signaling that induces apoptosis in T cells and cytokine secretion by monocytes. 4-1BB-L, the ligand for the co-stimulatory immune checkpoint receptor CD137/TNFRSF9/4-1BB, has been shown to reactivate anergic T lymphocytes in addition to promoting T lymphocyte proliferation. 4-1BB-L signaling through agonism at the 4-1BB receptor induces CD4+ and CD8+ T cells to proliferate and secrete cytokines. Provided as 25 μg of dry powder alongside reconstitution buffer.
Target Species:
Human
Usage
Product Type:
Recombinant Proteins
Application:
Drug Discovery & Development
Storage Conditions:
Store at -20°C. Please avoid multiple freeze/thaw cycles.
Usage disclaimer:
These products may be covered by issued US and/or foreign patents, patent applications and subject to a Limited Use Label License. Please visit discoverx.com/license for a list of products that are governed by limited use label license terms and relevant patent and trademark information.
Additional Information
Brand:
Eurofins DiscoverX®