Biological Information

Background Information:

The PrecisION™ rNav1.8 Recombinant Stable Cell Line is a stable, engineered cell line for use in studying rNav1.8 ion channels, including drug candidates which affect channel function. This cell line enables assessment of ion channel function via detection of electrophysiological signals. The included cell line overexpresses rNav1.8 ion channels. Upon ligand/agonist induced channel activation, response can be detected via automated or manual electrophysiological techniques.
This stable engineered cell line is provided as two vials of cryopreserved cells. Please note that this product expresses the rat version of the protein.

Target Class:

Ion Channel

Family:

Sodium

Sub Family:

Voltage-Gated

Protein Name:

Nav1.8

Protein Aliases:

Sensory neuron sodium channel|Peripheral nerve sodium channel 3

Accession Number:

U53833

UniProt Number:

Q62968

Gene Name:

Scn10a

Gene ID:

29571

Gene Aliases:

Nav1.8|hPN3|SNS|PN3

Target Species:

Rat

Cell Background:

ND7-23

Usage

Product Type:

Stable Cell Lines

Application:

Drug Discovery & Development

Storage Conditions:

Store in vapor phase of liquid nitrogen.

Usage disclaimer:

These products may be covered by issued US and/or foreign patents, patent applications and subject to a Limited Use Label License. Please visit discoverx.com/license for a list of products that are governed by limited use label license terms and relevant patent and trademark information.

Assay Information

Assay Type:

Cell Based

Assay Measures:

Electrophysiology

Detection Method:

Electrophysiology

Additional Information

Brand:

PrecisION™