Biological Information

Background Information:

PrecisION™ hERG (CHO-K1) Ready-to-Assay Frozen Cells provide an easy-to-use cell based assay to study hERG ion channels, including drug candidates which affect channel function. These Ready-To-Assay Frozen Cells enable assessment of ion channel function via detection of electrophysiological signals. The included cells overexpress hERG ion channels. Upon voltage-induced channel activation, response can be detected via automated or manual electrophysiological techniques. These cells are provided as single-use vials of cryopreserved cells.

Target Class:

Ion Channel

Family:

Potassium

Sub Family:

Voltage-Gated

Protein Name:

hERG

Protein Aliases:

Ether-a-go-go-related gene potassium channel 1|ERG-1|Eag-related protein 1|Ether-a-go-go-related protein 1|H-ERG|hERG-1|hERG1|Voltage-gated potassium channel subunit Kv11.1

Accession Number:

U04270

UniProt Number:

Q12809

Gene Name:

KCNH2

Gene ID:

3757

Gene Aliases:

Kv11.1|HERG|erg1

Target Species:

Human

Cell Background:

CHO-K1

Usage

Product Type:

Frozen Cells

Application:

Drug Discovery & Development

Storage Conditions:

Store in vapor phase of liquid nitrogen.

Usage disclaimer:

These products may be covered by issued US and/or foreign patents, patent applications and subject to a Limited Use Label License. Please visit discoverx.com/license for a list of products that are governed by limited use label license terms and relevant patent and trademark information.

Assay Information

Assay Type:

Cell Based

Assay Measures:

Electrophysiology

Detection Method:

Electrophysiology

Additional Information

Brand:

PrecisION™