Biological Information

Background Information:

The PathHunter® IL-15 Bioassay Kit (Dimerization) is a functional, robust, highly sensitive, and easy-to-use-cell based assay to study drug potency and neutralizing antibodies. This bioassay enables quantitation of IL-15 -Mediated Dimerization of the IL-15 receptor (IL2Rβ/IL2Rγ). Each PathHunter IL-15 bioassay kit contains all the materials needed to perform a complete assay, including cryopreserved, single-use cells, detection reagents, cell plating reagent, and assay plates. This bioassay has been optimized for a 96-well plate format.

Target Class:

Cytokine Receptor

Family:

IL-2 Receptor

Accession Number:

NM_000878.5; NM_000206.2

Target Species:

Human

Cell Background:

U2OS

Usage

Product Type:

Bioassay Kits

Application:

Potency, Commercial Release & Stability

Kit Components:

KitComponent

Storage Conditions:

Store in vapor phase of liquid nitrogen.

Usage disclaimer:

These products may be covered by issued US and/or foreign patents, patent applications and subject to a Limited Use Label License. Please visit discoverx.com/license for a list of products that are governed by limited use label license terms and relevant patent and trademark information.

Assay Information

Assay Type:

Cell Based

Assay Measures:

Dimerization

Detection Method:

Chemiluminescence

Clinical Relevance

Therapeutic Area:

Inflammation/Allergy

Additional Information

Brand:

PathHunter®