PAK1, active

Background Information:

This protein is a family member of serine/threonine p21-activating kinases, known as PAK proteins. These proteins are critical effectors that link to cytoskeleton reorganization and nuclear signaling, and they serve as targets for the small GTP binding proteins Cdc42 and Rac. This specific family member regulates cell motility and morphology. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Target Class:

Kinase

Family:

STE

Sub Family:

Protein Ser/Thr

Protein Name:

PAK1

Protein Aliases:

STE20 homolog, yeast

Accession Number:

NM_002576.4

UniProt Number:

Q13153

Gene Name:

PAK1

Gene ID:

5058

Target Species:

Human