Biological Information

Background Information:

N-terminal FLAG-tagged and C-terminal 10His-tagged, recombinant, full length human NEK10. NEK10 is a serine/threonine protein kinase belonging to the NEK Ser/Thr protein kinase family. The kinase regulates mucociliary transport in ciliated cells in airways and plays roles in mitochondrial homeostasis and the cellular response to UV irradition. Dysregulation or mutation of NEK10 has been associated with respiratory tract infections and various cancers.

Target Class:

Kinase

Family:

NEK Ser/Thr protein kinase

Sub Family:

Serine/threonine kinase

Protein Name:

NEK10

Protein Aliases:

NIMA related kinase 10

Accession Number:

GenBank NM_152534.6

UniProt Number:

Q6ZWH5

Gene Name:

NEK10

Gene ID:

152110

Gene Aliases:

CILD44

Target Species:

Human

Usage

Product Type:

Enzymes

Application:

Drug Discovery & Development

Storage Conditions:

1 year at -70°C

Usage disclaimer:

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Assay Information

Assay Type:

Enzymatic

Bioassay Data

Trademark Statement:

For Research Use Only

Clinical Relevance

Therapeutic Area:

Oncology/Immuno-Oncology