Biological Information

Background Information:

This protein is a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates various substrates, including CREB1 and ATF1. The protein can also phosphorylate histone H3 to regulate certain inflammatory genes. Several transcript variants encoding different isoforms have been found for this gene.

Target Class:

Kinase

Family:

AGC

Sub Family:

Protein Ser/Thr

Protein Name:

MSK2

Protein Aliases:

90 kDa ribosomal protein S6 kinase 4|Nuclear mitogen- and stress-activated protein kinase 2|Ribosomal protein kinase B|RSKB

Accession Number:

AJ010119.1

UniProt Number:

O75676

Gene Name:

RPS6KA4

Gene ID:

8986

Gene Aliases:

RSK-B|MSK2

Target Species:

Human

Usage

Product Type:

Enzymes

Application:

Drug Discovery & Development

Storage Conditions:

1 year at -70°C

Usage disclaimer:

These products may be covered by issued US and/or foreign patents, patent applications and subject to a Limited Use Label License. Please visit discoverx.com/license for a list of products that are governed by limited use label license terms and relevant patent and trademark information.

Assay Information

Assay Type:

Enzymatic

Bioassay Data

Trademark Statement:

For Research Use Only

Clinical Relevance

Therapeutic Area:

Oncology/Immuno-Oncology