MARK4, active

Background Information:

MARK4 is a member of the microtubule affinity-regulating kinase family. These protein kinases phosphorylate microtubule-associated proteins and regulate the transition between stable and dynamic microtubules. The encoded protein is associated with the centrosome throughout mitosis and may be involved in cell cycle control. Expression of this gene is a potential marker for cancer, and the encoded protein may also play a role in Alzheimer's disease. Pseudogenes of this gene are located on both the short and long arm of chromosome 3. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2010]

Target Class:

Kinase

Family:

CAMK

Sub Family:

Protein Ser/Thr

Protein Name:

MARK4

Protein Aliases:

MAP/microtubule affinity-regulating kinase-like 1

Accession Number:

NM_001199867.1

UniProt Number:

Q96L34

Gene Name:

MARK4

Gene ID:

57787

Gene Aliases:

Nbla00650|FLJ90097|KIAA1860|PAR-1D

Target Species:

Human