Biological Information
Background Information:
The KILR® CD16 Effector Cells are single donor-derived, human cytotoxic T lymphocytes that stably express CD16. They are intended for use as immune effector cells in antibody-dependent cell-mediated cytotoxicity (ADCC) or bi-specific antibody-mediated T-cell redirection (TCR) assays that measure cell death. The cells are produced in a standardized batch process to allow for high levels of assay reproducibility. This product is used with KILR® cell lines and pools in a co-culture model and can also be used in ADCC applications in place of other primary cells such as PBMCs or NK cells.
These effector cells are provided as a pack of five vials of cryopreserved cells and are shipped under vapor phase of liquid nitrogen.
Accession Number:
NM_000569.8
Target Species:
Human
Usage
Product Type:
Primary Cells
Application:
Cytotoxicity, Antibody-dependent Cell Cytotoxicity (ADCC), ADC-mediated Cytotoxicity
Storage Conditions:
Short term (24 h): Store in vapor phase of liquid nitrogen.
Usage disclaimer:
These products may be covered by issued US and/or foreign patents, patent applications and subject to a Limited Use Label License. Please visit discoverx.com/license for a list of products that are governed by limited use label license terms and relevant patent and trademark information.
Assay Information
Assay Type:
Cell Based
Assay Measures:
Cytotoxicity
Detection Method:
Chemiluminescence
Clinical Relevance
Therapeutic Area:
Oncology/Immuno-Oncology
Additional Information
Brand:
KILR®