Biological Information
Background Information:
IRE2 enables several functions, including ATP binding activity; magnesium ion binding activity; and protein serine/threonine kinase activity. IRE2 is also involved in several processes, including apoptotic chromosome condensation; negative regulation of transcription, DNA-templated; and rRNA catabolic process. Predicted to be located in endoplasmic reticulum membrane and endoplasmic reticulum quality control compartment. Predicted to be integral component of membrane. Predicted to be part of IRE1-TRAF2-ASK1 complex. [provided by Alliance of Genome Resources, Apr 2022]
Target Class:
Kinase
Family:
Other Protein Kinase
Sub Family:
Protein Ser/Thr
Protein Name:
IRE2
Accession Number:
NM_033266.2
UniProt Number:
Q76MJ5
Gene Name:
ERN2
Gene ID:
10595
Gene Aliases:
IRE1b
Target Species:
Human
Usage
Product Type:
Enzymes
Application:
Drug Discovery & Development
Storage Conditions:
1 year at -70°C
Usage disclaimer:
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Assay Information
Assay Type:
Enzymatic