InCELL Hunter™ eXpress CSNK1D Kinase Binding Assay

Background Information:

The InCELL Hunter™ eXpress CSNK1D Kinase Binding Assay provides an easy-to-use cell based assay to study small molecule drug candidates that engage with kinases. This kit assesses compound-engagement-based stabilization of CSNK1D via detection of CSNK1D levels. This product uses EFC technology. The cells included overexpress CSNK1D target protein fused to PL. In the absence of compound that binds and stabilizes the target, this protein is degraded and no EFC signal is produced. When compound engages and stabilizes the target, EA contained in the detection reagent produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates.

Target Class:

Kinase

Family:

CK1

Sub Family:

Protein Ser/Thr

Protein Name:

CK1delta

Protein Aliases:

CKId|Tau-protein kinase CSNK1D

Accession Number:

NC_000017.11

UniProt Number:

P48730

Gene Name:

CSNK1D

Gene ID:

1453

Gene Aliases:

HCKID|CKID|CKIdelta

Target Species:

Human

Cell Background:

A549