IKKalpha, active

Background Information:

The mammalian Abelson (Abl) family of non-receptor tyrosine kinases is comprised of c-Abl (ABL1) and Arg (Abl-related gene, ABL2), which are encoded by the Abl1 and Abl2 genes, respectively. Deregulation of the c-Abl and Arg tyrosine kinases can occur as a result of chromosomal translocation events that produce chimeric proteins associated with the development of human leukemias as well as gastric cancer invasion and progression.

Target Class:

Kinase

Family:

Other Protein Kinase

Sub Family:

Protein Ser/Thr

Protein Name:

IKKalpha

Protein Aliases:

IKK-A|IKK-alpha|IkBKA|IkappaB kinase|Conserved helix-loop-helix ubiquitous kinase|I-kappa-B kinase 1|IKK1|Nuclear factor NF-kappa-B inhibitor kinase alpha|NFKBIKA|Transcription factor 16|TCF-16

Accession Number:

NM_001278.3

UniProt Number:

O15111

Gene Name:

CHUK

Gene ID:

1147

Gene Aliases:

IKK1|IKK-alpha|IkBKA|NFKBIKA|IKKA|CHUK|TCF16

Target Species:

Human