Biological Information

Background Information:

DHX9 is a member of the DEAD-box RNA helicase family that unwinds RNA or DNA duplexes (or DNA:RNA hybrids) in an ATP-dependent manner. The helicase plays important roles in many cellular processes, including DNA replication, transcriptional activation, post-transcriptional RNA regulation, mRNA translation and RNA-mediated gene silencing. DHX9 has emerged as a significant player in tumorigenesis, infection and autoimmune diseases.

Target Class:

DEAD box helicase

Family:

DEAH

Sub Family:

RNA helicase

Protein Name:

DHX9

Protein Aliases:

ATP-dependent RNA helicase A

Accession Number:

GenBank NM_001357.5

UniProt Number:

Q08211

Gene Name:

DHX9

Gene ID:

1660

Gene Aliases:

LKP; RHA; DDX9; NDH2; MRD75; NDHII

Target Species:

Human

Usage

Product Type:

Enzymes

Application:

Drug Discovery & Development

Storage Conditions:

12 months at -70°C

Usage disclaimer:

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Assay Information

Assay Type:

Enzymatic

Clinical Relevance

Therapeutic Area:

Oncology/Immuno-Oncology