Biological Information
Background Information:
The Kinase Enzyme Activity Assay Kit is a biochemical assay for the measurement of kinase inhibitors. The kit uses the HitHunter® assay technology and has been optimized for COT1. All reagents are provided in the kit, including recombinant COT1 (Eurofins #16-059), substrate, ATP, detection reagents and assay plates. The COA that accompanies the kit details the optimal reaction conditions for the detection of kinase inhibitors. The kit includes sufficient material to run reactions for two 384-well assay plates.
Target Class:
Kinase
Family:
STE
Sub Family:
Serine/threonine kinase
Protein Name:
COUP-TF1
Protein Aliases:
COUP transcription factor I (COUP-TF I)|Nuclear receptor subfamily 2 group F member 1|V-erbA-related protein 3 (EAR-3)
Accession Number:
Z14138.1
UniProt Number:
P10589
Gene Name:
NR2F1
Gene ID:
7025
Gene Aliases:
EAR-3|COUP-TFI|TCFCOUP1|SVP44|COUPTF1|EAR3|BBOAS|BBSOAS|ERBAL3|TFCOUP1
Target Species:
Human
Usage
Product Type:
Enzyme Activity Assay Kits
Application:
Drug Discovery & Development
Storage Conditions:
1 year at -70°C
Usage disclaimer:
These products may be covered by issued US and/or foreign patents, patent applications and subject to a Limited Use Label License. Please visit discoverx.com/license for a list of products that are governed by limited use label license terms and relevant patent and trademark information.
Assay Information
Assay Measures:
ADP Accumulation
Detection Method:
Fluorescence
Clinical Relevance
Therapeutic Area:
Oncology/Immuno-Oncology/Inflammation
Additional Information
Brand: