Biological Information

Background Information:

CHIR-99021 HCl is a synthetic small molecule and ATP-competitive inhibitor of GSK3 kinase, with IC50 of 10 and 6.7nM for GSK3α and GSK3β, respectively. Has >500-fold selectivity for GSK3 over closely related CDC2 and ERK2 kinases. Functions as a WNT activator. Provided as 2 mg of dry powder.

Usage

Product Type:

Control Ligands & Inhibitors

Application:

Drug Discovery & Development

Storage Conditions:

Store at ≤-20°C. Please avoid multiple freeze/thaw cycles.

Usage disclaimer:

These products may be covered by issued US and/or foreign patents, patent applications and subject to a Limited Use Label License. Please visit discoverx.com/license for a list of products that are governed by limited use label license terms and relevant patent and trademark information.

Additional Information

Brand:

Eurofins DiscoverX®