Biological Information

Background Information:

The ChemiSCREEN™ FPRL1 N-Formylpeptide Receptor Membrane Preparation is derived from proprietary stable recombinant cells to ensure high levels of FPR2 surface expression. ChemiSCREEN™ membrane preps can be used to screen for GPCR activity using GTPγS assays. Increased GPCR activation levels will lead to higher radioactive signal. Membrane preps contain 1mL of 1mg/mL frozen membranes derived from a stably modified clonal cell line which was chosen for optimal receptor expression.

Target Class:

GPCR

Family:

Formylpeptide

Sub Family:

Class A

Protein Name:

FPR2

Protein Aliases:

FMLP-R-I|Formyl peptide receptor-like 1|HM63|Lipoxin A4 receptor|LXA4 receptor|RFP

Accession Number:

NM_001462

UniProt Number:

P25090

Gene Name:

FPR2

Gene ID:

2358

Gene Aliases:

LXA4R|HM63|FPRH2|FMLPX|FPR2A|FMLP-R-II|ALXR|FPR|FMLP

Target Species:

Human

Cell Background:

Chem-1

Usage

Product Type:

Membrane Preparations

Application:

Drug Discovery & Development

Storage Conditions:

Vial to be stored at -70°C. Avoid repeat freeze/thaw cycles.

Usage disclaimer:

These products may be covered by issued US and/or foreign patents, patent applications and subject to a Limited Use Label License. Please visit discoverx.com/license for a list of products that are governed by limited use label license terms and relevant patent and trademark information.

Assay Information

Assay Type:

Cell Based

Assay Measures:

GTPγS Function

Detection Method:

Fluorescence, Radioactivity

Additional Information

Brand:

ChemiSCREEN™