ChemiSCREEN™ CXCR7 Chemokine Receptor Membrane Preparation

Background Information:

The ChemiSCREEN™ CXCR7 Chemokine Receptor Membrane Preparation is derived from proprietary stable recombinant cells to ensure high levels of CXCR7 surface expression. ChemiSCREEN™ membrane preps can be used to screen for ligand binding affinities using a competitive radio-labeled ligand approach. Increased binding affinities will lead to higher radioactive signal. Membrane preps contain 1mL of 1mg/mL frozen membranes derived from a stably modified clonal cell line which was chosen for optimal receptor expression.

Target Class:

GPCR

Family:

Chemokine

Sub Family:

Class A

Protein Name:

ACKR3 (CXCR7)

Protein Aliases:

CXC-R7|CXCR-7|Chemokine orphan receptor 1|G-protein coupled receptor 159|G-protein coupled receptor RDC1 homolog|RDC-1

Accession Number:

NM_020311.2

UniProt Number:

P25106

Gene Name:

ACKR3

Gene ID:

57007

Gene Aliases:

CMKOR1|CXCR7|GPR159|RDC1

Target Species:

Human

Cell Background:

Chem-1