ChemiSCREEN™ CXCR4 Chemokine Receptor Membrane Preparation

Background Information:

The ChemiSCREEN™ CXCR4 Chemokine Receptor Membrane Preparation is derived from proprietary stable recombinant cells to ensure high levels of CXCR4 surface expression. ChemiSCREEN™ membrane preps can be used to screen for ligand binding affinities using a competitive radio-labeled ligand approach. Increased binding affinities will lead to higher radioactive signal. Membrane preps contain 1mL of 1mg/mL frozen membranes derived from a stably modified clonal cell line which was chosen for optimal receptor expression.

Target Class:

GPCR

Family:

Chemokine

Sub Family:

Class A

Protein Name:

CXCR4

Protein Aliases:

CXCR-4|Fusin|Leukocyte-derived seven transmembrane domain receptor|LESTR|Pre-B-cell-derived chemokine receptor|PB-CKR|Stromal cell-derived factor 1 receptor|SDF-1 receptor|CD antigen CD184

Accession Number:

M99293

UniProt Number:

P61073

Gene Name:

CXCR4

Gene ID:

7852

Gene Aliases:

LESTR|NPY3R|HM89|NPYY3R|D2S201E|fusin|HSY3RR|NPYR|CD184

Target Species:

Human

Cell Background:

Chem-1