Biological Information

Background Information:

The ChemiSCREEN™ CCR2B Chemokine Receptor Membrane Preparation is derived from proprietary stable recombinant cells to ensure high levels of CCR2 surface expression. ChemiSCREEN™ membrane preps can be used to screen for ligand binding affinities using a competitive radio-labeled ligand approach. Increased binding affinities will lead to higher radioactive signal. Membrane preps contain 1mL of 1mg/mL frozen membranes derived from a stably modified clonal cell line which was chosen for optimal receptor expression.

Target Class:

GPCR

Family:

Chemokine

Sub Family:

Class A

Protein Name:

CCR2

Protein Aliases:

CC-CKR-2|CCR-2|CCR2|Monocyte chemoattractant protein 1 receptor|MCP-1-R|CD antigen CD192

Accession Number:

NM_001123396

UniProt Number:

P41597

Gene Name:

CCR2

Gene ID:

729230

Gene Aliases:

CC-CKR-2|CKR2|MCP-1-R|CD192|FLJ78302

Target Species:

Human

Cell Background:

Chem-1

Usage

Product Type:

Membrane Preparations

Application:

Drug Discovery & Development

Storage Conditions:

Vial to be stored at -70°C. Avoid repeat freeze/thaw cycles.

Usage disclaimer:

These products may be covered by issued US and/or foreign patents, patent applications and subject to a Limited Use Label License. Please visit discoverx.com/license for a list of products that are governed by limited use label license terms and relevant patent and trademark information.

Assay Information

Assay Type:

Cell Based

Assay Measures:

Binding

Detection Method:

Fluorescence, Radioactivity

Additional Information

Brand:

ChemiSCREEN™