Biological Information
Background Information:
The ChemiSCREEN™ BLT1 Leukotriene Receptor Membrane Preparation is derived from proprietary stable recombinant cells to ensure high levels of LTB4R surface expression. ChemiSCREEN™ membrane preps can be used to screen for ligand binding affinities using a competitive radio-labeled ligand approach. Increased binding affinities will lead to higher radioactive signal. Membrane preps contain 1mL of 1mg/mL frozen membranes derived from a stably modified clonal cell line which was chosen for optimal receptor expression.
Target Class:
GPCR
Family:
Leukotriene
Sub Family:
Class A
Protein Name:
BLT1 (LTB4)
Protein Aliases:
LTB4-R1|Chemoattractant receptor-like 1|G-protein coupled receptor 16|P2Y purinoceptor 7|P2Y7
Accession Number:
D89078
UniProt Number:
Q15722
Gene Name:
LTB4R
Gene ID:
1241
Gene Aliases:
BLT|BLT1|BLTR|CMKRL1|GPR16|P2RY7
Target Species:
Human
Cell Background:
Chem-1
Usage
Product Type:
Membrane Preparations
Application:
Drug Discovery & Development
Storage Conditions:
Vial to be stored at -70°C. Avoid repeat freeze/thaw cycles.
Usage disclaimer:
These products may be covered by issued US and/or foreign patents, patent applications and subject to a Limited Use Label License. Please visit discoverx.com/license for a list of products that are governed by limited use label license terms and relevant patent and trademark information.
Assay Information
Assay Type:
Cell Based
Assay Measures:
Binding
Detection Method:
Fluorescence, Radioactivity
Additional Information
Brand:
ChemiSCREEN™