Biological Information

Background Information:

The Kinase Enzyme Activity Assay Kit is a biochemical assay for the measurement of kinase inhibitors. The kit uses the HitHunter® assay technology and has been optimized for CDKL5. All reagents are provided in the kit, including recombinant CDKL5 (Eurofins #14-998), substrate, ATP, detection reagents and assay plates. The COA that accompanies the kit details the optimal reaction conditions for the detection of kinase inhibitors. The kit includes sufficient material to run reactions for six 384-well assay plates.

Target Class:

Kinase

Family:

CMGC

Sub Family:

Serine/threonine kinase

Protein Name:

CDKL5

Protein Aliases:

Serine/threonine-protein kinase 9

Accession Number:

NM_003159.3

UniProt Number:

O76039

Gene Name:

CDKL5

Gene ID:

6792

Gene Aliases:

EIEE2|CFAP247

Target Species:

Human

Usage

Product Type:

Enzyme Activity Assay Kits

Application:

Drug Discovery & Development

Storage Conditions:

1 year at -70°C

Usage disclaimer:

These products may be covered by issued US and/or foreign patents, patent applications and subject to a Limited Use Label License. Please visit discoverx.com/license for a list of products that are governed by limited use label license terms and relevant patent and trademark information.

Assay Information

Assay Measures:

ADP Accumulation

Detection Method:

Fluorescence

Bioassay Data

Trademark Statement:

For Research Use Only

Clinical Relevance

Therapeutic Area:

Developmental disorders

Additional Information

Brand: