Biological Information

Background Information:

The Kinase Enzyme Activity Assay Kit is a biochemical assay for the measurement of kinase inhibitors. The kit uses the HitHunter® assay technology and has been optimized for CDK15/cyclin Y. All reagents are provided in the kit, including recombinant CDK15/cyclin Y (Eurofins #14-996), substrate, ATP, detection reagents and assay plates. The COA that accompanies the kit details the optimal reaction conditions for the detection of kinase inhibitors. The kit includes sufficient material to run reactions for twenty five 384-well assay plates.

Target Class:

Kinase

Family:

CMGC (CDK, MAPK, GSK, CLK, DYRK, SRPK)

Sub Family:

Serine/threonine kinase

Protein Name:

CDK15

Protein Aliases:

Cyclin-dependent kinase 15

Accession Number:

GenBank NM_139158.1 (CDK15); GenBank BC094815.1 (cyclin Y)

UniProt Number:

Q96Q40

Gene Name:

CDK15

Gene ID:

65061

Gene Aliases:

PFTK2; ALS2CR7; PFTAIRE2

Target Species:

Human

Usage

Product Type:

Enzyme Activity Assay Kits

Application:

Drug Discovery & Development

Storage Conditions:

12 months at -70°C

Usage disclaimer:

These products may be covered by issued US and/or foreign patents, patent applications and subject to a Limited Use Label License. Please visit discoverx.com/license for a list of products that are governed by limited use label license terms and relevant patent and trademark information.

Assay Information

Assay Type:

Enzymatic

Clinical Relevance

Therapeutic Area:

Oncology