Biological Information

Background Information:

Complex of N-Terminal GST-tagged, recombinant, human, full length CDK15 and N-Terminal GST-tagged, recombinant, human, full length Cyclin Y, co-expressed in insect cells. CDK15/cyclin Y is a serine/threonine protein kinase that acts as an anti-apoptotic protein. Recent studies suggest that the kinase promotes colorectal cancer and some breast cancers.

Target Class:

Kinase

Family:

CMGC (CDK, MAPK, GSK, CLK, DYRK, SRPK)

Sub Family:

Serine/threonine kinase

Protein Name:

CDK15/cyclin Y

Protein Aliases:

cyclin dependent kinase 15

Accession Number:

GenBank NM_139158.1 (CDK15) / GenBank BC094815.1 (cyclin Y)

UniProt Number:

Q96Q40

Gene Name:

CDK15

Gene ID:

65061

Gene Aliases:

PFTK2; ALS2CR7; PFTAIRE2

Target Species:

Human

Usage

Product Type:

Enzymes

Application:

Drug Discovery & Development

Storage Conditions:

1 year at -70°C

Usage disclaimer:

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Assay Information

Assay Type:

Enzymatic

Bioassay Data

Trademark Statement:

For Research Use Only

Clinical Relevance

Therapeutic Area:

Oncology/Immuno-Oncology