Casein Kinase 2alpha2, active

Background Information:

Casein Kinase 2 Alpha 2 is a catalytic subunit of a constitutively active serine/threonine-protein kinase complex that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine. It phosphorylates acidic proteins such as casein, and is involved in various cellular processes, including cell cycle control, apoptosis, and circadian rhythms. This heterotetrameric kinase includes two catalytic subunits, either alpha or alpha', and two regulatory beta subunits. The closely related gene paralog encoding the alpha, or alpha 1 subunit (CSNK2A1, Gene ID: 1457) is found on chromosome 20. An intronic variant in this gene (alpha 2) may be associated with leukocyte telomere length in a South Asian population. A related transcribed pseudogene is found on chromosome 11. GenBank NM_001896

Target Class:

Kinase

Family:

Other Protein Kinase

Sub Family:

Protein Ser/Thr

Protein Name:

CK2alpha2

Protein Aliases:

casein kinase 2 alpha'

Accession Number:

NM_001896.2

UniProt Number:

P19784

Gene Name:

CSNK2A2

Gene ID:

1459

Gene Aliases:

CSNK2A1|CK2alpha'|CK2A2

Target Species:

Human