cAMP Hunter™ Exenatide Bioassay Kit

Background Information:

The cAMP Hunter™ Exenatide Bioassay kit provides an easy-to-use cell based assay to measure drug potency and detect neutralizing antibodies. This bioassay assesses ligand (e.g. Exendin-4) based activation of GLP1R GPCR activity via detection of levels of intracellular cAMP. The bioassay kit contains all the materials needed for a complete assay, including cells, detection reagents, cell plating reagent, assay plates, and for some kits, a positive control agonist. The ready-to-use cryopreserved cells have been manufactured to ensure assay reproducibility and faster implementation from characterization to lot release. This bioassay has been optimized for a 96-well format.

Please reach out to Tech Support at DiscoverXSupportUS@discovery.eurofinsus.com for lot specific CoA.

Target Class:

GPCR

Family:

Glucagon

Sub Family:

Class B

Protein Name:

GLP-1

Protein Aliases:

GLP-1-R|GLP-1R

Accession Number:

NM_002062.3

UniProt Number:

P43220

Gene Name:

GLP1R

Gene ID:

2740

Target Species:

Human

Cell Background:

CHO-K1