BMPR2, active

Background Information:

Bone Morphogenetic Protein Receptor Type 2 (BMPR2) is a member of the bone morphogenetic protein receptor family of transmembrane serine/threonine kinases. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of two different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Mutations in this gene have been associated with primary pulmonary hypertension, both familial and fenfluramine-associated, and with pulmonary venoocclusive disease. [provided by RefSeq, May 2020]

Target Class:

Kinase

Family:

TKL

Sub Family:

Protein Ser/Thr

Protein Name:

BMPR2

Protein Aliases:

BMPR-2|Bone morphogenetic protein receptor type II|BMP type II receptor|BMPR-II

Accession Number:

NM001204.7

UniProt Number:

Q13873

Gene Name:

BMPR2

Gene ID:

659

Gene Aliases:

BRK-3|T-ALK|BMPR3|BMPR-II

Target Species:

Human