BIKe, active

Background Information:

This gene is the human homolog of mouse BMP-2-inducible kinase. Bone morphogenic proteins (BMPs) play a key role in skeletal development and patterning. Expression of the mouse gene is increased during BMP-2 induced differentiation and the gene product is a putative serine/threonine protein kinase containing a nuclear localization signal. Therefore, the protein encoded by this human homolog is thought to be a protein kinase with a putative regulatory role in attenuating the program of osteoblast differentiation. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Target Class:

Kinase

Family:

NAK

Sub Family:

Protein Ser/Thr

Protein Name:

BIKE

Accession Number:

NM017593.3

UniProt Number:

Q9NSY1

Gene Name:

BMP2K

Gene ID:

55589

Gene Aliases:

BIKE|HRIHFB2017

Target Species:

Human