Biological Information

Background Information:

On ligand binding, ALK4 forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. GenBank NM_004302

Target Class:

Kinase

Family:

RSTK

Sub Family:

Protein Ser/Thr

Protein Name:

ALK4

Protein Aliases:

Activin receptor type IB|ACTR-IB|Activin receptor-like kinase 4|ALK-4|Serine/threonine-protein kinase receptor R2|SKR2

Accession Number:

NM_004302.3; NM_020327.2; NM_020328.2

UniProt Number:

P36896

Gene Name:

ACVR1B

Gene ID:

91

Gene Aliases:

ALK4|SKR2|ActRIB|ACVRLK4

Target Species:

Human

Usage

Product Type:

Enzymes

Application:

Drug Discovery & Development

Storage Conditions:

1 year at -70°C

Usage disclaimer:

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Assay Information

Assay Type:

Enzymatic

Bioassay Data

Trademark Statement:

For Research Only

Clinical Relevance

Therapeutic Area:

Oncology/Immuno-Oncology