TAO2, active

Background Information:

TAOK2 (TAO Kinase 2) is a serine/threonine protein kinase that is involved in many different processes, including, cell signaling, microtubule organization and stability, and apoptosis. TAO2 is involved in different processes such as membrane blebbing and apoptotic bodies formation DNA damage response and MAPK14/p38 MAPK stress-activated MAPK cascade. In response to DNA damage, TAO2 is involved in the G2/M transition DNA damage checkpoint by activating the p38/MAPK14 stress-activated MAPK cascade, probably by mediating phosphorylation of upstream MAP2K3 and MAP2K6 kinases. GenBank NM_016151

Target Class:

Kinase

Family:

STE

Sub Family:

Protein Ser/Thr

Protein Name:

TAO2

Protein Aliases:

Kinase from chicken homolog C|hKFC-C|Prostate-derived sterile 20-like kinase 1|PSK-1|PSK1|Prostate-derived STE20-like kinase 1|Thousand and one amino acid protein kinase 2

Accession Number:

NM_004783.2; NM_016151.2

UniProt Number:

Q9UL54

Gene Name:

TAOK2

Gene ID:

9344

Gene Aliases:

TAO1|KIAA0881|PSK|PSK1|TAO2|MAP3K17

Target Species:

Human