Biological Information
Background Information:
TAE684 (NVP-TAE684) is a synthetic potent and selective inhibitor of the kinase ALK (IC50=3nM) as well as FLT3 and TIE2 (IC50=3nM and 12nM, respectively). It is 100 times more selective for ALK than InsR, and is effective at inhibiting the NPM-ALK fusion protein responsible for survival and proliferation of anaplastic large-cell lymphomas (ALCLs). Provided as 5 mg of dry powder.
Usage
Product Type:
Control Ligands & Inhibitors
Application:
Drug Discovery & Development
Storage Conditions:
Store at ≤-20°C. Please avoid multiple freeze/thaw cycles.
Usage disclaimer:
These products may be covered by issued US and/or foreign patents, patent applications and subject to a Limited Use Label License. Please visit discoverx.com/license for a list of products that are governed by limited use label license terms and relevant patent and trademark information.
Additional Information
Brand:
Eurofins DiscoverX®