Biological Information
Background Information:
The PrecisION™ hKCNQ1/hminK Recombinant Stable Cell Line is a stable, engineered cell line for use in studying KCNQ1/hminK ion channels, including drug candidates which affect channel function. This cell line enables assessment of ion channel function via detection of electrophysiological signals. The included cell line overexpresses KCNQ1/hminK ion channels. Upon ligand/agonist induced channel activation, response can be detected via automated or manual electrophysiological techniques.
This stable engineered cell line is provided as two vials of cryopreserved cells.
Target Class:
Ion Channel
Family:
Potassium
Sub Family:
Voltage-Gated
Protein Name:
KCNQ1
Protein Aliases:
Jervell and Lange-Nielsen syndrome 1
Accession Number:
AF000571
UniProt Number:
P51787
Gene Name:
KCNQ1
Gene ID:
3784
Gene Aliases:
Kv7.1|KCNA8|KVLQT1|JLNS1|LQT1
Target Species:
Human
Cell Background:
CHO-K1
Usage
Product Type:
Stable Cell Lines
Application:
Drug Discovery & Development
Storage Conditions:
Store in vapor phase of liquid nitrogen.
Usage disclaimer:
These products may be covered by issued US and/or foreign patents, patent applications and subject to a Limited Use Label License. Please visit discoverx.com/license for a list of products that are governed by limited use label license terms and relevant patent and trademark information.
Assay Information
Assay Type:
Cell Based
Assay Measures:
Electrophysiology
Detection Method:
Electrophysiology
Additional Information
Brand:
PrecisION™