Biological Information

Background Information:

N-terminal GST-tagged, recombinant, full length, human PRKG2. PRKG2 is a member of the serine/threonine protein kinase family. Crucial regulator of intestinal secretion and bone growth. Acts downstream of NMDAR to activate the plasma membrane accumulation of GRIA1/GLUR1 in synapse and increase synaptic plasticity. Acts as regulator of gene expression and activator of the extracellular signal-regulated kinases MAPK3/ERK1 and MAPK1/ERK2 in mechanically stimulated osteoblasts.

Target Class:

Kinase

Family:

AGC

Sub Family:

Serine/threonine kinase

Protein Name:

PKG2

Protein Aliases:

cGK2|cGMP-dependent protein kinase II|cGKII

Accession Number:

BC111597.2

UniProt Number:

Q13237

Gene Name:

PRKG2

Gene ID:

5593

Gene Aliases:

cGKII|PRKGR2

Target Species:

Human

Usage

Product Type:

Enzymes

Application:

Drug Discovery & Development

Storage Conditions:

1 year at -70°C

Usage disclaimer:

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Bioassay Data

Trademark Statement:

For Research Use Only

Clinical Relevance

Therapeutic Area:

Oncology/Immuno-Oncology