Biological Information
Background Information:
The ERBB family of receptor tyrosine kinases, namely the EGF receptor (EGFR), ERBB2/HER2/Neu, ERBB3, and ERBB4, regulate cellular proliferation, differentiation, and programmed cell death in a growth factor-dependent manner. ERBBs mediate signaling by a large number of growth factors that are structurally related to EGF such as transforming growth factor-a or amphiregulin. GenBank NM_005235
Target Class:
Kinase
Family:
RTK
Sub Family:
Protein Tyrosine
Protein Name:
HER4
Protein Aliases:
human epidermal growth factor receptor 4
Accession Number:
NM_001005915.1; NM_001982.2
UniProt Number:
Q15303
Gene Name:
ERBB4
Gene ID:
2066
Gene Aliases:
ALS19|HER4
Target Species:
Human
Usage
Product Type:
Enzymes
Application:
Drug Discovery & Development
Storage Conditions:
1 year at -70°C
Usage disclaimer:
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Assay Information
Assay Type:
Enzymatic
Bioassay Data
Trademark Statement:
For Research Use Only
Clinical Relevance
Therapeutic Area:
Oncology/Immuno-Oncology