ChemiSCREEN™ ETB Endothelin Receptor Membrane Preparation

Background Information:

The ChemiSCREEN™ ETB Endothelin Receptor Membrane Preparation is derived from proprietary stable recombinant cells to ensure high levels of EDNRB surface expression. ChemiSCREEN™ membrane preps can be used to screen for ligand binding affinities using a competitive radio-labeled ligand approach. Increased binding affinities will lead to higher radioactive signal. Membrane preps contain 1mL of 2mg/mL frozen membranes derived from a stably modified clonal cell line which was chosen for optimal receptor expression.

Target Class:

GPCR

Family:

Endothelin

Sub Family:

Class A

Protein Name:

ETB

Protein Aliases:

ET-BR|Endothelin receptor non-selective type

Accession Number:

NM_000115

UniProt Number:

P24530

Gene Name:

EDNRB

Gene ID:

1910

Gene Aliases:

ETB

Target Species:

Human

Cell Background:

CHO-K1