Biological Information
Background Information:
Anti-VISTA Antibody [730804] is a mouse monoclonal antibody that detects human VISTA/B7-H5/PD-1H. VISTA (V-domain Ig suppressor of T cell activation), also known as platelet receptor Gi24, is a member of the Ig superfamily and is a transmembrane molecule expressed in bone, on embryonic stem cells (ESCs), and on tumor cell surfaces. Gi24 interacts with BMP-4, potentiating BMP signaling and the transition from an undifferentiated to a differentiated state; and promotes MT1-MMP expression and activity and serves as a substrate for MT1-MMP. Provided as 25 μg of antibody in 50μL buffer.
Target Class:
Checkpoint Receptor
Usage
Product Type:
Antibodies
Application:
Drug Discovery & Development
Storage Conditions:
Store at -20°C. Please avoid multiple freeze/thaw cycles.
Usage disclaimer:
These products may be covered by issued US and/or foreign patents, patent applications and subject to a Limited Use Label License. Please visit discoverx.com/license for a list of products that are governed by limited use label license terms and relevant patent and trademark information.
Additional Information
Brand:
Eurofins DiscoverX®