Search results: “PD-1”

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Qualification Data PD-1 Signaling Bioassay Kit Qualification Data

Webinars Establishing Qualified Bioassays for Checkpoint Receptors to Implement in QC Lot Release: Case Studies on PD-1 and SIRPα

Regulation of immune responses is tightly controlled through a balance of co-stimulatory and inhibitory checkpoint receptors, which is often exploited…

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Scientific Posters Improved Cell-Based Assays To Assess Therapeutic Molecules Against Immune Checkpoint Receptors Such As PD-1, PD-L1 and PD-L2

Regulation of immune responses is tightly controlled through a balance of co-stimulatory and inhibitory checkpoint receptors, often exploited by many…

Scientific Posters New PathHunter Reporter Assays: Analysis of PD-1 Checkpoint Receptor and NFAT Signaling Pathways

Reporter genes are a well-established method used to develop cell-based assays for testing drugs that inhibit targets involved in specific…

Application Notes Automating Cell-Based Bioassay on Tecan®’s Fluent Automation Workstation: Measuring PD-1 Signaling

An Application Note on automating Eurofins DiscoverX Cell-Based PathHunter® PD-1 Signaling Bioassay to bring high-throughput efficiencies to assay workflows. The…

Presentations [PEGS 2024] Fast-tracking Checkpoint Antibody Development with MOA-Reflective Assays for Cancer & Autoimmune Therapeutics

Checkpoint blockade antibodies are established cancer therapeutics. However, in recent years, agonistic antibodies have emerged as therapeutics not only for…

Videos Reporter Assays for Therapeutics Targeting Signaling Pathways

Learn how PathHunter signaling reporter assays can be used to evaluate the cellular impact of therapeutics targeting a variety of…

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Case Studies Evaluating Checkpoint Receptor Bioassays: Fit-For-Purpose Assays Intended for Potency Testing of Therapeutic Candidates in QC Lot Release

Ready-to-Use qualified PathHunter® checkpoint bioassays are fit-forpurpose for potency testing for implementation in downstream development phases and Lot release of…

Scientific Posters Immuno-Oncology Therapeutics Development Using PathHunter Signaling Pathway Reporter Assays

Reporter genes are a well-established method used to develop cell-based assays for testing drugs that inhibit or activate targets involved…