| Biological Information | |
|---|---|
| Background Information: | TrkC is a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signaling through this kinase leads to cell differentiation and may play a role in the development of proprioceptive neurons that sense body position. Mutations in this gene have been associated with medulloblastomas, secretory breast carcinomas and other cancers. Several transcript variants encoding different isoforms have been found for this gene. |
| Target Class: | Kinase |
| Accession Number: | NM_002530 |
| Target Name: | TrkC |
| Target Aliases: | TRKCNTRK3Trk-C |
| Target Species: | Human |
| Usage | |
| Product Type: | Enzymes |
| Application: | Drug Discovery & Development |
| Storage Conditions: | 6 months at -70°C |
| Usage Disclaimer: | These products may be covered by issued US and/or foreign patents, patent application and subject to Limited Use Label License. Please visit discoverx.com/license for a list of products that are governed by limited use label license terms and relevant patent and trademark information. |
TrkC, active
10 µg of active TrkC. N-terminal GST-tagged and C-terminal 6His-tagged recombinant, human TrkC amino acids 510-end.
Datasheets
14-922x Datasheet
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