PrecisION® hnAChR alpha4/beta2 Recombinant Stable Cell Line

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The PrecisION® hnAChR α4/β2 Recombinant Stable Cell Line measures nAChR α4/β2 ion channel activity via electrophysiological measurements. This cell line ships as two vials of cryopreserved cells.

Catalog #: CYL3106 Size: 2 vials
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Biological Information
Background Information:
The PrecisION® hnAChR α4/β2 Recombinant Stable Cell Line is a stable, engineered cell line for use in studying nAChR α4/β2 ion channels, including drug candidates which affect channel function. This cell line enables assessment of ion channel function via detection of electrophysiological signals. The included cell line overexpresses nAChR α4/β2 ion channels. Upon ligand/agonist induced channel activation, response can be detected via automated or manual electrophysiological techniques. This stable modified cell line is provided as two vials of cryopreserved cells.
Target Class:
Ion Channel
Family:
Ligand-Gated Nicotinic Receptor
Accession Number:
NM_000744.6/NM_000748.2
Target Name:
nAChR α4/β2
Target Aliases:
EBN, EBN1, NARAC, neuronal acetylcholine receptor subunit alpha-4, Acra4, BFNC, Neuronal, α-bungarotoxin-insensitive, cholinergic receptor, nicotinic, alpha 4 (neuronal), cholinergic receptor, nicotinic alpha 4, cholinergic receptor
Target Species:
Human
Usage
Product Type:
Stable Cell Lines
Application:
Drug Discovery & Development
Storage Conditions:
Store in vapor phase of liquid nitrogen.
Usage Disclaimer:
These products may be covered by issued US and/or foreign patents, patent application and subject to Limited Use Label License. Please visit discoverx.com/license for a list of products that are governed by limited use label license terms and relevant patent and trademark information.
Assay Information
Assay Measures:
Electrophysiology
Additional Information
Brand:
PrecisION®

User Manuals & Protocols

70-430 PrecisION Ion Channel Cell Lines_Rev_2.0

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Datasheets

CYL3106 Datasheet

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