| Biological Information | |
|---|---|
| Background Information: | Pim-3 (Proviral integration site for Moloney murine leukemia virus 3) is a serine/threonine protein kinase that belongs to the Pim family of kinases. It is involved in a variety of cellular processes, including cell proliferation, survival, differentiation, and metabolism.
Research has suggested that Pim-3 plays a role in several diseases, including cancer, cardiovascular diseases, and inflammatory disorders. It has been shown to promote cancer cell proliferation and survival, and inhibition of Pim-3 has been suggested as a potential cancer therapy. Additionally, Pim-3 has been implicated in the regulation of T-cell development and function, making it a potential target for the treatment of autoimmune diseases and graft-versus-host disease. |
| Target Class: | Kinase |
| Family: | PIM Family |
| Accession Number: | NM_001001852.2 |
| Target Name: | PIM3 |
| Target Aliases: | PIM3, pim-3 |
| Target Species: | Human |
| Usage | |
| Product Type: | Enzymes |
| Application: | Drug Discovery & Development |
| Storage Conditions: | 6 months at -70°C |
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Pim-3, active
N-terminal 6His-tagged recombinant, human Pim-3.
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14-738x Datasheet
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