| Biological Information | |
|---|---|
| Background Information: | MRCKα Protein is a member of the Serine/Threonine protein kinase family. This kinase contains multiple functional domains. Its kinase domain is highly similar to that of the myotonic dystrophy protein kinase (DMPK). This kinase also contains a Rac interactive binding (CRIB) domain, and has been shown to bind CDC42. It may function as a CDC42 downstream effector mediating CDC42 induced peripheral actin formation, and promoting cytoskeletal reorganization. Multiple alternatively spliced transcript variants have been described, and the full-length nature of two of them has been reported.
GenBank NM_003607 |
| Target Class: | Kinase |
| Accession Number: | NM_003607.3; NM_014826.4 |
| Target Name: | MRCKα |
| Target Aliases: | CDC42BPADKFZp686L1738PK428DKFZp686P1738KIAA0451FLJ23347MRCKMRCKA |
| Target Species: | Human |
| Usage | |
| Product Type: | Enzymes |
| Application: | Drug Discovery & Development |
| Storage Conditions: | 6 months at -70°C |
| Usage Disclaimer: | These products may be covered by issued US and/or foreign patents, patent application and subject to Limited Use Label License. Please visit discoverx.com/license for a list of products that are governed by limited use label license terms and relevant patent and trademark information. |
MRCKalpha, active
C-terminal 6His-tagged recombinant, human MRCKα amino acids 1-473.
Datasheets
14-691x Datasheet
View Document