| Biological Information | |
|---|---|
| Background Information: | MKK6/SKK3 Protein is a member of the dual specificity protein kinase family, which functions as a mitogen-activated protein (MAP) Kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein phosphorylates and activates p38 MAP kinase in response to inflammatory cytokines or environmental stress. As an essential component of p38 MAP kinase mediated signal transduction pathway, this gene is involved in many cellular processes such as stress induced cell cycle arrest, transcription activation and apoptosis.
EMBL U39657 |
| Target Class: | Kinase |
| Family: | Ser/Thr Kinase; MAPK; STE7 Family |
| Accession Number: | NM_002758.3 |
| Target Name: | MKK6 |
| Target Aliases: | MAP2K6, PRKMK6, MEK6, SAPKK3, MAPKK6, MKK6 |
| Target Species: | Human |
| Usage | |
| Product Type: | Enzymes |
| Application: | Drug Discovery & Development |
| Storage Conditions: | 6 months at -70°C |
| Usage Disclaimer: | These products may be covered by issued US and/or foreign patents, patent application and subject to Limited Use Label License. Please visit discoverx.com/license for a list of products that are governed by limited use label license terms and relevant patent and trademark information. |
MKK6/SKK3 (S599D, T603D), active
N-terminal MBP-tagged recombinant, human MKK6/SKK3 amino acids 4-end containing S599D and T603D mutations.
Datasheets
14-537x Datasheet
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